Reactions in borderline leprosy.
Indian J Lepr
;
2002 Apr-Jun; 74(2): 115-28
Artigo
em Inglês
| IMSEAR
| ID: sea-54374
ABSTRACT
This is a retrospective study of 276 patients consisting of 157 active and 119 reactive patients of borderline leprosy. They were followed up for 10 years after sulphone monotherapy. The presenting symptoms were carefully examined from the records and systematically presented. Frequency of reactions was least in BT cases and most in BL cases. Risk factors of reaction appear to be the type of leprosy, multiplicity of lesions, high BI and, possibly, psychological stress. Biopsy of skin lesions was performed in all cases initially, and at the subsidence of the disease. Histological findings closely correlated with clinical classification. While all the cases showed clinical subsidence, histological subsidence was found in 200 (73%) cases, and the condition was static in 36 cases (13%). Immunological upgrading was seen in 110%, while 4% showed downgrading. Bacteriological status and lepromin reaction of active and reactive cases were compared. All these factors need to be taken into consideration for instituting prompt and proper treatment.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Nervos Periféricos
/
Biópsia
/
Feminino
/
Humanos
/
Masculino
/
Hanseníase Dimorfa
/
Hanseníase Virchowiana
/
Hanseníase Tuberculoide
/
Estudos Retrospectivos
/
Seguimentos
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Idioma:
Inglês
Revista:
Indian J Lepr
Assunto da revista:
Tropical Medicine
Ano de publicação:
2002
Tipo de documento:
Artigo
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