Histological and immunological correlates of suspected leprosy lesions.
Indian J Lepr
;
1996 Apr-Jun; 68(2): 155-9
Artigo
em Inglês
| IMSEAR
| ID: sea-54882
ABSTRACT
Thirty-two subjects with suspected leprosy lesions were investigated to assess various modalities of sensibility and sweat function and these were correlated with immunological and histological parameters. It was found that pain and temperature, mediated by small unmyelinated fibres were impaired in the early lesions. Impairment of sweat function was seen only when one of the modalities of sensibility was also affected. Antibodies specific to a protein (35 kDa) antigen and phenolic glycolipid 1 of Mycobacterium leprae were positive in nine and 12 cases respectively, while 15 of the 31 biopsies revealed the presence of mycobacterial antigens in these lesions. The implications of these findings are discussed.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Sudorese
/
Sensação Térmica
/
Feminino
/
Humanos
/
Masculino
/
Criança
/
Limiar da Dor
/
Adulto
/
Antígeno de Mitsuda
/
Hanseníase
Idioma:
Inglês
Revista:
Indian J Lepr
Assunto da revista:
Tropical Medicine
Ano de publicação:
1996
Tipo de documento:
Artigo
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