Ultrastructural study of epidermal Langherhans cells in leprosy.
Indian J Lepr
;
1984 Oct-Dec; 56(4): 840-3
Artigo
em Inglês
| IMSEAR
| ID: sea-55401
ABSTRACT
ATPase staining and ultrastructural study of skin biopsies from six patients of leprosy (2TT, 4LL) and three normal subjects was carried out to study Langherhans Cells (LC). ATPase staining showed normal counts of LCs in tuberculoid patients, while significant reduction was observed in lepromatous cases. Electron microscopy revealed morphological changes in LL cases in the form of dense matrix and indistinct cristae of mitochondria; decreased number of lysosomes and rough endoplasmic reticulum; and numerous vacuoles in cytoplasm. TT cases showed normal morphology. Possible role of Langerhans Cells in pathogenesis of leprosy is discussed.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Pele
/
Humanos
/
Microscopia Eletrônica
/
Células de Langerhans
/
Hanseníase
Idioma:
Inglês
Revista:
Indian J Lepr
Assunto da revista:
Tropical Medicine
Ano de publicação:
1984
Tipo de documento:
Artigo
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