Neoplastic transformation of chronic ulcers in leprosy patients--a retrospective study of 23 consecutive cases.
Indian J Lepr
;
1998 Apr-Jun; 70(2): 179-87
Artigo
em Inglês
| IMSEAR
| ID: sea-55440
ABSTRACT
A retrospective analysis of chronic ulcers among leprosy patients seen over the last 20 years yielded 23 cases of neoplastic transformation. It showed a peak at the sixth decade, an incidence of 3.66/100 among hospitalised ulcer cases and male/female ratio of 1.61. Borderline tuberculoid was the most common type of leprosy involved (40%). Squamous cell carcinoma was the most common neoplasia. Its usual site was plantar ulcers. Heel ulcers showed relatively greater predeliction for malignancy (38.5%). Histopathological proof of malignancy is desirable and that may require multiple biopsies. Metastasis is rare but potentially fatal. The surgical treatment must provide a functional, trouble-free limb. Forefoot or Lisfranc's amputation for distal third ulcers and below-knee amputation for large midfoot and ulcers are procedures of choice. Wide excision may be used in select cases.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Recidiva
/
Neoplasias Cutâneas
/
Idoso
/
Feminino
/
Humanos
/
Masculino
/
Carcinoma de Células Escamosas
/
Transformação Celular Neoplásica
/
Doença Crônica
/
Incidência
Tipo de estudo:
Estudo de incidência
/
Estudo observacional
/
Estudo prognóstico
Idioma:
Inglês
Revista:
Indian J Lepr
Assunto da revista:
Tropical Medicine
Ano de publicação:
1998
Tipo de documento:
Artigo
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