Assessment of viability by normal mouse foot-pad and bacillary ATP bioluminescence assay in multibacillary cases treated with an MDT regimen using conventional as well as newer drugs like minocycline and ofloxacin.
Indian J Lepr
;
2000 Oct-Dec; 72(4): 437-42
Artigo
em Inglês
| IMSEAR
| ID: sea-55473
ABSTRACT
The therapeutic effect of a drug regimen of conventional drugs as well as newer drugs like ofloxacin and minocycline in smear-positive multibacillary (MB) leprosy cases was assessed by mouse foot-pad and ATP bioluminiscence methods. Biopsies were taken before starting treatment and after one year of treatment. They were processed for viability assessment by normal mouse foot-pad inoculation and bacillary ATP assay techniques. The test regimen was quite effective in its anti-bacterial effect as it was found to result in loss of bacillary viability in all the cases, as assessed by both methods.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Humanos
/
Trifosfato de Adenosina
/
Resultado do Tratamento
/
Pé
/
Hansenostáticos
/
Hanseníase
/
Medições Luminescentes
/
Animais
/
Camundongos
/
Mycobacterium leprae
Idioma:
Inglês
Revista:
Indian J Lepr
Assunto da revista:
Tropical Medicine
Ano de publicação:
2000
Tipo de documento:
Artigo
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