Adenosine deaminase activity in leprosy.
Indian J Lepr
;
1990 Oct-Dec; 62(4): 473-7
Artigo
em Inglês
| IMSEAR
| ID: sea-55559
ABSTRACT
Adenosine deaminase (ADA) activity was studied in serum and peripheral blood lymphocytes of leprosy patients and healthy controls. Serum ADA levels were found to be elevated in tuberculoid as well as lepromatous cases compared to control subjects. Serum ADA activity was significantly higher in tuberculoid cases than in the lepromatous group. Lymphocyte adenosine deaminase activity showed a similar trend. These results suggest that, since the overall activity of the enzyme is not deficient in leprosy, the cellular immune abberation seen in the different types of leprosy may be due to abnormal proliferation of different subsets of lymphocytes in response to M. leprae.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Humanos
/
Ativação Linfocitária
/
Linfócitos
/
Hanseníase Virchowiana
/
Hanseníase Tuberculoide
/
Adenosina Desaminase
/
Mycobacterium leprae
Idioma:
Inglês
Revista:
Indian J Lepr
Assunto da revista:
Tropical Medicine
Ano de publicação:
1990
Tipo de documento:
Artigo
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