Characterization of leprosy based on the nasal lipid profile.
Indian J Lepr
;
1997 Apr-Jun; 69(2): 179-81
Artigo
em Inglês
| IMSEAR
| ID: sea-55592
ABSTRACT
While extracting the M. leprae from the nasal flushings of leprosy patients it was found that these organisms were trapped in the waxy layer, between the aqueous and the chloroform layers. Thin layer chromotography (TLC) analysis of this layer, using chloroform-methanol-water system, revealed different spots when sprayed with acid alcohol and heated at 160 degrees C. The TLC profile of lipids of lepromatous and borderline (MB according to the WHO terminology) leprosy patients was distinctly different from that of tuberculoid leprosy patients and normal human volunteers. A simple, economical and fast procedure to characterize patients belonging to different spectra has been developed.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Humanos
/
Cromatografia em Camada Fina
/
Diagnóstico Diferencial
/
Metabolismo dos Lipídeos
/
Hanseníase
/
Mycobacterium leprae
/
Mucosa Nasal
Tipo de estudo:
Estudo diagnóstico
Idioma:
Inglês
Revista:
Indian J Lepr
Assunto da revista:
Tropical Medicine
Ano de publicação:
1997
Tipo de documento:
Artigo
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