Effect of cisplatin, rIFN-Y, LPS and MDP on release of H2O2, O2- and lysozyme from human monocytes in vitro.
Indian J Exp Biol
;
1991 Oct; 29(10): 910-5
Artigo
em Inglês
| IMSEAR
| ID: sea-55777
ABSTRACT
Increased secretion of H2O2, O2- and lysozyme by human monocytes in vitro on treatment with cisplatin, rIFN-Y (interferon-Y), LPS (lipopolysaccharide) and MDP (muramyl dipeptide) is reported. It is suggested that increased production of these secretory products represent the activated state of monocytes. These in vitro activated monocytes could either kill the tumor cells via increased contact mediated cytolysis or cytolysis mediated via the release of the secretory products like H2O2, O2- and lysozyme.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Peróxidos
/
Fatores de Tempo
/
Proteínas Recombinantes
/
Humanos
/
Monócitos
/
Muramidase
/
Acetilmuramil-Alanil-Isoglutamina
/
Lipopolissacarídeos
/
Interferon gama
/
Cisplatino
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
1991
Tipo de documento:
Artigo
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