Active immunization of rats with chicken egg thiamin carrier protein results in early embryonic loss at periimplantation stages.
Indian J Exp Biol
;
1996 Apr; 34(4): 302-6
Artigo
em Inglês
| IMSEAR
| ID: sea-56296
ABSTRACT
Active immunization with chicken egg white thiamin carrier protein (TCP) was performed to assess the functional importance of the vitamin carrier during gestation in rats. Towards this, fertile female rats were immunized with heterologous TCP and when the circulatory titres of anti-TCP IgG were high, these animals were mated with fertile male rats. Progression of pregnancy was monitored by measuring circulatory progesterone levels. A sudden fall in the steroid hormonal levels around day 8 post coitus was observed. Histological examination of the uterine tissue sections on day 7 revealed that active immunization with TCP affected the blastocyst viability resulting in unsuccessful implantation and hence pregnancy termination.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Implantação do Embrião
/
Ratos
/
Tiamina
/
Feminino
/
Masculino
/
Gravidez
/
Proteínas de Transporte
/
Proteínas do Ovo
/
Galinhas
/
Ratos Wistar
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
1996
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS