2-(2,3-dimethylchromon-6-yl) propanoic acid (OVS-103): a potent anti-inflammatory agent.
Indian J Exp Biol
;
1995 Nov; 33(11): 841-4
Artigo
em Inglês
| IMSEAR
| ID: sea-56561
ABSTRACT
The compound OVS-103 showed dose-dependent anti-inflammatory and anti-arthritic effects in different acute and chronic test models in rats and mice. It produced inhibition of the exudate volume and the migration of leucocytes in the carrageenan induced pleurisy test in rats. OVS-103 showed poor inhibitory effect on granuloma formation induced by cotton pellet and had no anti-pyretic and analgesic property. ALD50 in both rats and mice was more than 2000 mg/kg, p.o. and 1500 mg/kg, i.p.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Pleurisia
/
Artrite
/
Ratos
/
Útero
/
Feminino
/
Gravidez
/
Permeabilidade Capilar
/
Anti-Inflamatórios não Esteroides
/
Cromonas
/
Modelos Animais de Doenças
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
1995
Tipo de documento:
Artigo
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