Chlorpyrifos induced alterations in levels of thiobarbituric acid reactive substances and glutathione in rat brain.
Indian J Exp Biol
;
2001 Feb; 39(2): 174-7
Artigo
em Inglês
| IMSEAR
| ID: sea-56718
ABSTRACT
Chlorpyrifos, O,O'-diethyl-O-3,5,6-trichloro-2-pyridyl phosphorothionate, exposure in rats caused significant inhibition of acetylcholinesterae activity in different regions of brain and generated oxidative stress as evidenced by increase in the level of thiobarbituric acid reactive substances and decrease in the ratio of reduced to oxidized glutathione in all the three regions of brain. Malondialdehyde level was increased significantly in all regions of brain and the increase was dose dependent. Mid brain showed highest level of lipid peroxidation.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Ratos
/
Encéfalo
/
Masculino
/
Peroxidação de Lipídeos
/
Substâncias Reativas com Ácido Tiobarbitúrico
/
Ratos Wistar
/
Clorpirifos
/
Glutationa
/
Inseticidas
/
Animais
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
2001
Tipo de documento:
Artigo
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