Lindane mediated induction of cytochrome P-450 mRNA in rat liver: studies with a nonradioactive cDNA probe.
Indian J Exp Biol
;
1989 Aug; 27(8): 729-31
Artigo
em Inglês
| IMSEAR
| ID: sea-57029
ABSTRACT
Effect of lindane on the induction of cytochrome P-450 mRNA in rat liver was studied using a biotinylated cDNA probe. Exposure to lindane resulted in an increase in the levels of P-450 mRNA. The observed increase in mRNA was maximal (5-6-fold) after 18 hr of lindane treatment and lesser (50%) than mediated by phenobarbital for the same duration.
Texto completo:
DisponíveL
Índice:
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Assunto principal:
Ratos
/
Ratos Endogâmicos
/
Hexaclorocicloexano
/
Masculino
/
RNA Mensageiro
/
Sondas de DNA
/
Sistema Enzimático do Citocromo P-450
/
Fígado
/
Animais
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
1989
Tipo de documento:
Artigo
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