Effect of malathion on antioxidant defence system in human fetus--an in vitro study.
Indian J Exp Biol
;
1992 Apr; 30(4): 352-4
Artigo
em Inglês
| IMSEAR
| ID: sea-57152
ABSTRACT
Malathion under in vitro condition even at lower concentration (250 ppm) altered the level of enzymes associated with glutathione cycle and antioxidant defence system in human fetal brain and liver. Such changes involved alterations in glutathione status and extent of lipid peroxidation. The inhibitory effect of malathion was dose dependent in case of human fetal brain and was more vulnerable than fetal liver. This alteration (inhibition or activation) was maximum in case of tissues from fetuses of early period of development, suggesting greater susceptibility of human fetus towards this organophosphorus insecticide.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Encéfalo
/
Humanos
/
Fatores Etários
/
Idade Gestacional
/
Feto
/
Fígado
/
Malation
/
Antioxidantes
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
1992
Tipo de documento:
Artigo
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