Suppression of Con A induced lymphocyte transformation by sera from filarial patients with clinical manifestations.
Indian J Exp Biol
;
1991 Apr; 29(4): 352-4
Artigo
em Inglês
| IMSEAR
| ID: sea-57390
ABSTRACT
Reduced lymphocyte transformation to Wuchereria bancrofti microfilariae excretory-secretory antigen and Con A were observed in clinical filarial patients. Pre-incubation of normal human peripheral blood mononuclear cells with sera from filarial patients with clinical manifestations such as hydrocele and elephantiasis suppressed Con A induced responses. Effect of fractionated clinical filarial serum on Con A induced lymphocyte transformation showed that the inhibitory activity was associated with high molecular weight serum fraction.
Texto completo:
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Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Wuchereria bancrofti
/
Filariose Linfática
/
Humanos
/
Ativação Linfocitária
/
Células Cultivadas
/
Concanavalina A
/
Tolerância Imunológica
/
Animais
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
1991
Tipo de documento:
Artigo
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