Swerchirin induced blood sugar lowering of streptozotocin treated hyperglycemic rats.
Indian J Exp Biol
;
1991 Jul; 29(7): 674-5
Artigo
em Inglês
| IMSEAR
| ID: sea-57520
ABSTRACT
Effect of Swerchirin (18 dihydroxy 35 dimethoxy xanthone) isolated from hexane fraction of Swertia chirayita on the blood sugar level of healthy and streptozotocin treated rats was studied. Streptozotocin was administered in citrate buffer (pH-4.5) intravenously / 35 and 65 mg/kg body wt to Charles Foster strain albino rats. Swerchirin (50 mg/kg, po) suspended in gum acacia was fed through cannula to the above rats and to a group of healthy rats. Blood sugar estimated at 0, 1, 3 and 7 hr after, indicated a very significant lowering in healthy and streptozotocin (35 mg/kg iv) but not in streptozotocin (65 mg/kg) treated rats.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Ratos
/
Xantenos
/
Glicemia
/
Masculino
/
Estreptozocina
/
Xantonas
/
Diabetes Mellitus Experimental
/
Hiperglicemia
/
Hipoglicemiantes
/
Animais
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
1991
Tipo de documento:
Artigo
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