Pulmonary vasospasm in rabbits infused with stroma free haemoglobin solution.
Indian J Exp Biol
;
1989 Mar; 27(3): 265-8
Artigo
em Inglês
| IMSEAR
| ID: sea-57876
ABSTRACT
Effect of infusion of stroma free haemoglobin solution into mice and rabbits was studied. Though no abnormalities were noted in mice, pulmonary vasospasm and hepatocytic necrosis were seen in all rabbits. In addition to reports that low adenosine deaminase levels in the solution could be a cause of vasoconstriction, it is proposed on the basis of present results that either denaturation of haemoglobin molecule itself or release of super oxide anion during oxygenation of haemoglobin, could cause cellular damage leading to toxicity.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Coelhos
/
Vasoconstrição
/
Infusões Intravenosas
/
Feminino
/
Masculino
/
Hemoglobinas
/
Circulação Pulmonar
/
Fígado
/
Animais
/
Camundongos
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
1989
Tipo de documento:
Artigo
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