Permeation through cornea.
Indian J Exp Biol
;
2001 Jan; 39(1): 11-24
Artigo
em Inglês
| IMSEAR
| ID: sea-58349
ABSTRACT
The permeability of the cornea to drugs is clinically important because it is the major factor determining the efficacy of topically applied ophthalmic preparations. With this perspective, the present article gives a brief update and overview of corneal structure and proposed mechanisms of permeation. Physiological, physicochemical and formulation factors affecting drug permeation through cornea are highlighted. Influence of ocular penetration enhancers on drug permeation is also discussed.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Permeabilidade
/
Humanos
/
Farmacocinética
/
Córnea
/
Animais
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
2001
Tipo de documento:
Artigo
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