Effect of piracetam on electroshock induced amnesia and decrease in brain acetylcholine in rats.
Indian J Exp Biol
;
1993 Oct; 31(10): 822-4
Artigo
em Inglês
| IMSEAR
| ID: sea-58475
ABSTRACT
Piracetam, a prototype of a new class of psychotropic agents, the nootropic agents, which improve learning ability and memory retention, was found to induce a dose-related prevention of disruption of acquisition of a passive avoidance response produced by electroshock application. The amnesia attenuating effect of piracetam was accompanied by prevention of the decrease in acetylcholine concentrations of rat brain induced by electroshock. The study indicates that the cognition enhancing effect of piracetam may be due to a facilitatory effect on cholinergic transmission.
Texto completo:
DisponíveL
Índice:
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Assunto principal:
Piracetam
/
Ratos
/
Encéfalo
/
Masculino
/
Acetilcolina
/
Ratos Wistar
/
Transmissão Sináptica
/
Eletrochoque
/
Amnésia
/
Animais
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
1993
Tipo de documento:
Artigo
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