Effect of insecticidal crystal proteins of Bacillus thuringiensis on human erythrocytes in vitro.
Indian J Exp Biol
;
1996 Dec; 34(12): 1241-4
Artigo
em Inglês
| IMSEAR
| ID: sea-58624
ABSTRACT
Effect of intact and alkali solubilized insecticidal crystal protein (ICP) preparations from a mutant strain of B. thuringiensis var. israelensis (VCRC MB24) and the wild type strain (VCRC B17) in vitro on human erythrocytes with respect to lipid peroxidation, osmofragility and membrane bound enzymes was determined. The alkali solubilized ICPs of both B. thuringiensis strains caused increased lipid peroxidation, decreased resistance to hypotonic lysis and reduction in the activity of membrane bound enzymes. On the contrary, the intact ICPs did not produce any such adverse effect on RBCs under the same experimental conditions. It is suggested that the ICPs are safe when they are intact when compared with solubilized ones.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Fragilidade Osmótica
/
Bacillus thuringiensis
/
Proteínas de Bactérias
/
Toxinas Bacterianas
/
Humanos
/
Controle Biológico de Vetores
/
Endotoxinas
/
Eritrócitos
/
Proteínas Hemolisinas
/
Inseticidas
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
1996
Tipo de documento:
Artigo
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