Modulatory effect of quercetin on azathioprine induced membrane changes in the mouse spleen.
Indian J Exp Biol
;
2001 Feb; 39(2): 132-6
Artigo
em Inglês
| IMSEAR
| ID: sea-58626
ABSTRACT
Modulatory effect of quercetin on azathioprine induced toxic changes was studied in spleen of experimental animals. Azathioprine treatment caused an increase in serum albumin/globin ratio and a decrease in total protein in spleen tissue. An increase in a membrane bound ATPases was also noted. Supplementation of quercetin with azathioprine increased the protein content and lowered the activities of membrane ATPase in spleen. There was a decrease in serum albumin globulin ratio. It was concluded that quercetin modulated the protein and membrane bound ATPase activities and protected the spleen from azathioprine induced membrane damage.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Quercetina
/
Baço
/
Azatioprina
/
Masculino
/
Albumina Sérica
/
Membrana Celular
/
Adenosina Trifosfatases
/
Globulinas
/
Animais
/
Camundongos
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
2001
Tipo de documento:
Artigo
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