Effect of nitric oxide on H+ -efflux in presence of various nutrients in Candida albicans.
Indian J Exp Biol
;
2004 Jan; 42(1): 86-90
Artigo
em Inglês
| IMSEAR
| ID: sea-58679
ABSTRACT
In the present study tentative link has been established between H+ -efflux and effect of NO in presence of various nutrients (glucose, 2-deoxy-D-glucose, xylose, proline, glutamic acid and lysine) in C. albicans using sodium nitroprusside (SNP) as a potent source of NO. It was observed that there was a decreasing trend in pH with time, in control, while SNP treated cells showed an initial decline in pH for 10-15 min, followed by an increase in pH up to 30 min. In presence of glucose there was an enhancement in H+ -efflux by 9-fold whereas proline, glutamic acid and lysine showed enhancement by 3, 6 and 1.5-fold respectively. Similar trends in increase in pH after 15 min in SNP treated cells of Candida was observed in presence of all nutrients used. It was demonstrated for the first time that H+ -ATPase of C. albicans was affected by NO.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Prótons
/
Fatores de Tempo
/
Transporte Biológico
/
Candida albicans
/
Nitroprussiato
/
Trifosfato de Adenosina
/
ATPases Translocadoras de Prótons
/
Adenosina Trifosfatases
/
Concentração de Íons de Hidrogênio
/
Íons
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
2004
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS