Fructose, 1,6-diphosphate mitigates CCl4 suppressed nitric oxide synthase activity in rats.
Indian J Exp Biol
;
2001 Jan; 39(1): 68-9
Artigo
em Inglês
| IMSEAR
| ID: sea-58720
ABSTRACT
Effect of fructose 1,6-diphosphate (FDP) and carbon tetrachloride (CCl4) were studied individually and in combination on rat endothelial (ET) and smooth muscle cell (SMC) nitric oxide synthase (NOS) activities in vivo, inhibition of ET and SMC NOS activity in CCl4 treated rats was reversed in FDP + CCl4 treated animals. Cellular based NOS activity was significantly increased in FDP treated group of rats when compared to non treated controls. The results suggest a significant increase in NOS in rats treated with a combination of FDP + CCl4 thus overcoming the suppression of NOS exposed to CCl4 alone.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Ratos
/
Tetracloreto de Carbono
/
Óxido Nítrico Sintase
/
Endotélio
/
Frutosedifosfatos
/
Animais
/
Músculo Liso
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
2001
Tipo de documento:
Artigo
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