Role of 5-hydroxytryptamine in Moringa oleifera induced potentiation of pentobarbitone hypnosis in albino rats.
Indian J Exp Biol
;
2004 Jun; 42(6): 632-5
Artigo
em Inglês
| IMSEAR
| ID: sea-58833
ABSTRACT
The role of 5-hydroxytryptamine (5-HT) in pentobarbitone (PB) sleeping time, gross behaviour, electrical activity of the brain and serum 5-HT level was studied in Holtzman strain adult albino rats following treatment with M. oleifera (MO). MO (350mg/kg) caused inhibition of awareness, touch response, motor activity, righting reflex, and grip strength. It significantly increased the PB sleeping time, serum 5-HT level (P<0.001) and alpha-wave activity. These observations indicate that the aqueous extract of MO potentiated PB induced sleeping time and increased the alpha-wave activity through 5-HT.
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Índice:
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Assunto principal:
Pentobarbital
/
Ratos
/
Sono
/
Fatores de Tempo
/
Comportamento Animal
/
Encéfalo
/
Feminino
/
Masculino
/
Serotonina
/
Sequestradores de Radicais Livres
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
2004
Tipo de documento:
Artigo
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