Decreased activity of hepatic alkaline protease in rats with carbon tetrachloride-induced liver cirrhosis.
Indian J Exp Biol
;
1999 Dec; 37(12): 1243-4
Artigo
em Inglês
| IMSEAR
| ID: sea-59261
ABSTRACT
To investigate the cause of accumulation of oxidised proteins in the livers of rats with carbon tetrachloride (CCl4) induced liver cirrhosis, the activity of alkaline protease (a high molecular weight, multisubunit cysteine proteinase) was determined in the cirrhotic livers. A significant decrease (P < 0.05) in the activity of hepatic alkaline protease was observed in the cirrhotic rats. Decreased activity of alkaline protease in the liver of cirrhotic rats may contribute to the accumulation of the oxidised proteins in the liver.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Oxirredução
/
Ratos
/
Masculino
/
Tetracloreto de Carbono
/
Proteínas
/
Ratos Wistar
/
Fígado
/
Cirrose Hepática Experimental
/
Animais
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
1999
Tipo de documento:
Artigo
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