Potentiality of a new compound for in vitro differentiation between halophilic and non-halophilic vibrios.
Indian J Exp Biol
;
2002 Feb; 40(2): 220-2
Artigo
em Inglês
| IMSEAR
| ID: sea-59323
ABSTRACT
Sensitivity of 21 halophilic vibrios and 16 clinical isolates of non-halophilic vibrios was determined against a new possible antivibrio agent, a pyrimidine analogue, 4, 6-dimethylpyrimidine -2-thiol (4,6-DMPT). It appeared to be a vibriocidal agent, having a mean MIC and MBC of 32 microg/ml for halophilic strains and 64 microg/ml for non-halophilic strains and an LD50 of 300 mg/Kg body weight of mice. Thus, 4,6-DMPT may help an in vitro distinction between halophilic and non-halophilic vibrios. Sensitivity of these strains was also studied with respect to pteridine, crystal violet and Tween 80 hydrolysis as further markers distinguishing between these 2 groups which could also be differentiated by their growth on TCBS or/and CLED media.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Polissorbatos
/
Pteridinas
/
Pirimidinas
/
Tensoativos
/
Vibrio cholerae
/
Vibrio parahaemolyticus
/
Testes de Sensibilidade Microbiana
/
Sensibilidade e Especificidade
/
Violeta Genciana
/
Hidrólise
Tipo de estudo:
Estudo diagnóstico
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
2002
Tipo de documento:
Artigo
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