Effect of thyroidectomy on fast and slow muscle fibres of rat gastrocnemius muscle.
Indian J Exp Biol
;
2000 Jun; 38(6): 575-9
Artigo
em Inglês
| IMSEAR
| ID: sea-60158
ABSTRACT
A combined histochemical, biochemical and electrophoretic study with respect to the enzymes succnic dehydrogenase(SDH), myofibrillar adenosine triphosphatase (m-ATPase), lactate dehydrogenase (LDH) isozymes and myosin light chains was carried out to investigate the response of rat gastrocnemius muscle (medial head). Twelve weeks after thyroidectomy, the results indicated a shift from fast to slow type pattern of LDH isozymes, fibre type transformation from Type II to Type I and a decrease in SDH and m-ATPase activity. The results suggest, possible thyroidal involvement in determining the phenotypic properties of skeletal muscle.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Ratos
/
Succinato Desidrogenase
/
Tireoidectomia
/
Masculino
/
Adenosina Trifosfatases
/
Fibras Musculares de Contração Lenta
/
Fibras Musculares de Contração Rápida
/
Cadeias Leves de Miosina
/
Hipotireoidismo
/
Isoenzimas
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
2000
Tipo de documento:
Artigo
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