Inhibition of selenium dependent glutathione peroxidase and superoxide dismutase in rats by diethyldithiocarbamate: effect of pre-administration of alpha-tocopherol.
Indian J Exp Biol
;
2007 May; 45(5): 465-8
Artigo
em Inglês
| IMSEAR
| ID: sea-60172
ABSTRACT
Rats pre-administered with alpha-tocopherol (10 mgs/day) for 7 days afforded a significant protection at the tissue level against the lowering of superoxide dismutase and glutathione peroxidase, especially the selenium-dependent glutathione peroxidase. The protective action of alpha-tocopherol in the diethyldithiocarbamate treated rats may be attributed to its antioxidant/free radical scavenging action. It is concluded that selenium-dependent glutathione peroxidase and alpha-tocopherol act in a complementary fashion to block free radical formation.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Ratos
/
Superóxido Dismutase
/
Fatores de Tempo
/
Masculino
/
Ratos Wistar
/
Ditiocarb
/
Citoproteção
/
Alfa-Tocoferol
/
Radicais Livres
/
Glutationa Peroxidase
Tipo de estudo:
Estudos de avaliação
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
2007
Tipo de documento:
Artigo
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