Effect of antidiabetic compounds on glyoxalase I activity in experimental diabetic rat liver.
Indian J Exp Biol
;
1999 Feb; 37(2): 193-5
Artigo
em Inglês
| IMSEAR
| ID: sea-60174
ABSTRACT
The activity of glyoxalase I from the soluble fraction of diabetic rat liver was found to decrease as compared to the control. Sodium orthovanadate in drinking water and Trigonella foenum graecum seed powder when administered to these diabetic animals were found to reverse the activity of glyoxalase I to control values. A combination of the above two antidiabetic compounds showed a better reversal. Vanadate and Trigonella seed powder treatment separately to diabetic rats also normalized hyperglycemia together with glyoxalase I activity. A combination of vanadate and Trigonella seed powder also restored the other general parameters of the diabetic animals.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Plantas Medicinais
/
Ratos
/
Feminino
/
Vanadatos
/
Extratos Vegetais
/
Ratos Wistar
/
Trigonella
/
Diabetes Mellitus Experimental
/
Hipoglicemiantes
/
Lactoilglutationa Liase
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
1999
Tipo de documento:
Artigo
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