Reversal of endothelin-1-induced contractions by isoproterenol without myosin dephosphorylation in tracheal smooth muscle.
Indian J Exp Biol
;
1992 Mar; 30(3): 252-4
Artigo
em Inglês
| IMSEAR
| ID: sea-60478
ABSTRACT
Effects of isoproterenol on isometric force, and 20,000 Da myosin light chain (LC20) phosphorylation were examined in smooth muscle fibre strips from lamb trachea stimulated with endothelin-1 (ET-1). ET-1 induced a rapidly rising isometric tension which was coupled with a multiple site phosphorylation of LC20. Isoproterenol addition at the time of peak isometric force resulted in a brisk relaxation of the fibre strips. Myosin light chain phosphorylation, however, remained unaffected.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Fosforilação
/
Traqueia
/
Ovinos
/
Endotelinas
/
Miosinas
/
Isoproterenol
/
Animais
/
Contração Muscular
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
1992
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS