Effect of 3-[p-(N-2-pyrimidylsulfamoyl)phenyl hydrazono]pentane-2,4-dione on blood parameters of albino rats.
Indian J Exp Biol
;
1996 Oct; 34(10): 982-6
Artigo
em Inglês
| IMSEAR
| ID: sea-60541
ABSTRACT
Intramuscular injection of 3-[p-(N-2-pyrimidylsulfamoyl)phenylhydrazono]pentane-2,4-dio ne (compound I) resulted in decrease in haemoglobin and alanine transaminase (ALT) and increase in aspartate transaminase (AST) values in albino rats. The serum glucose was found to decrease and after administration of 14 doses of 5.4 mg kg-1 body wt glucose level also declined significantly. It is concluded that the compound I is a better hypoglycemic than sulfonamide or hydrazone alone.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Pirimidinas
/
Aspartato Aminotransferases
/
Ratos
/
Glicemia
/
Nitrogênio da Ureia Sanguínea
/
Masculino
/
Alanina Transaminase
/
Hipoglicemiantes
/
Dose Letal Mediana
/
Animais
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
1996
Tipo de documento:
Artigo
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