Effect of alpha,beta-arteether against primary amoebic meningoencephalitis in Swiss mice.
Indian J Exp Biol
;
1998 Aug; 36(8): 824-5
Artigo
em Inglês
| IMSEAR
| ID: sea-61193
ABSTRACT
Artemisinin and its derivative alpha, beta-arteether have been evaluated for activity against experimental primary amoebic meningoencephalitis. In vivo experiments have shown that amphotericin B at dose of 2.5 mg/kg for 5 days produced 100% protection. Artemisinin and alpha, beta-arteether, even when tested at a high doses (60-120 mg/kg x 5 days and 90-180 mg/x 5 days) respectively, were not curative and showed only slight protection as indicated by extension of mean survival time.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Sesquiterpenos
/
Anfotericina B
/
Naegleria fowleri
/
Artemisininas
/
Amebíase
/
Amebicidas
/
Animais
/
Meningoencefalite
/
Camundongos
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
1998
Tipo de documento:
Artigo
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