Biochemical changes in kidneys of normal and stone forming rats with L(+)-tartrate.
Indian J Exp Biol
;
1990 Nov; 28(11): 1046-9
Artigo
em Inglês
| IMSEAR
| ID: sea-61309
ABSTRACT
Influence of L(+)-tartrate was studied on certain enzymes, protein bound carbohydrates and lipids in the renal tissues of experimentally induced stone forming rats. The elevation in kidney LDH was moderate in the stone forming groups while tartrate had no effect. The significant increases in the activities of (Na+, K+)- and (Ca2+)-ATPases in the calculogenic group was lowered to that of normal level with tartrate administration. Acid phosphatase activity was significantly lowered in the tartrate treated groups. The significant reduction in phospholipids and elevation in sialic acid levels during stone formation are suggestive of minor alterations in the cellular structure. The changes in the transport ATPases is likely to affect the transport mechanism of nutrients and ions.
Texto completo:
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Índice:
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Assunto principal:
Ratos
/
Ratos Endogâmicos
/
Tartaratos
/
Masculino
/
Cálculos Urinários
/
Adenosina Trifosfatases
/
Rim
/
L-Lactato Desidrogenase
/
Animais
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
1990
Tipo de documento:
Artigo
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