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Biochemical changes in kidneys of normal and stone forming rats with L(+)-tartrate.
Indian J Exp Biol ; 1990 Nov; 28(11): 1046-9
Artigo em Inglês | IMSEAR | ID: sea-61309
ABSTRACT
Influence of L(+)-tartrate was studied on certain enzymes, protein bound carbohydrates and lipids in the renal tissues of experimentally induced stone forming rats. The elevation in kidney LDH was moderate in the stone forming groups while tartrate had no effect. The significant increases in the activities of (Na+, K+)- and (Ca2+)-ATPases in the calculogenic group was lowered to that of normal level with tartrate administration. Acid phosphatase activity was significantly lowered in the tartrate treated groups. The significant reduction in phospholipids and elevation in sialic acid levels during stone formation are suggestive of minor alterations in the cellular structure. The changes in the transport ATPases is likely to affect the transport mechanism of nutrients and ions.
Assuntos
Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Assunto principal: Ratos / Ratos Endogâmicos / Tartaratos / Masculino / Cálculos Urinários / Adenosina Trifosfatases / Rim / L-Lactato Desidrogenase / Animais Idioma: Inglês Revista: Indian J Exp Biol Ano de publicação: 1990 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Assunto principal: Ratos / Ratos Endogâmicos / Tartaratos / Masculino / Cálculos Urinários / Adenosina Trifosfatases / Rim / L-Lactato Desidrogenase / Animais Idioma: Inglês Revista: Indian J Exp Biol Ano de publicação: 1990 Tipo de documento: Artigo