Lectin mediated binding of Streptococcus pyogenes to human oropharyngeal mucosal epithelial cells.
Indian J Exp Biol
;
1996 Mar; 34(3): 270-1
Artigo
em Inglês
| IMSEAR
| ID: sea-61523
ABSTRACT
The study was carried out to determine the role of lectins and sugars in the adhesion of S. pyogenes to human pharyngeal and buccal epithelial cells. In vitro adhesion assay has shown that Con A and Dolicos biflorus lectins inhibited the attachment of S. pyogenes to the oropharyngeal mucosal cells. Among different sugars used, N-acetyl-D-galactosamine and D-galactose have significantly blocked the binding of streptococci to PEC and BEC. These findings indicate that lectins and sugar molecules mediate the adhesion of S. pyogenes to the pharyngeal epithelial cells which may be important in the cellular pathogenesis of streptococcal infections which originate at the human oropharyngeal mucosa.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Faringe
/
Ligação Proteica
/
Streptococcus pyogenes
/
Humanos
/
Células Epiteliais
/
Lectinas
/
Mucosa Bucal
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
1996
Tipo de documento:
Artigo
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