Prolactin suppression during pre and post-implantation periods on rat uterine glucosamine synthase activity.
Indian J Exp Biol
;
1993 Apr; 31(4): 386-8
Artigo
em Inglês
| IMSEAR
| ID: sea-61551
ABSTRACT
Administration of bromocriptine (Bc), an ergot derivative having dopamine receptor agonist activity, to rats on day 1-5 of pregnancy prevented implantation of blastocysts and significantly suppressed uterine glucosamine 6-phosphate synthase activity. There was no effect on implantation or the enzyme activity when Bc was injected on day 7 or later of pregnancy. Injection of prolactin following Bc partially restored the enzyme activity and increased number of implantation sites. These results indicate that suppression of prolactin on day 1 to 5 of pregnancy causes failure of implantation. Bc on day 9 or later had no effect possibly due to the availability of placental LH/hCG to support the luteal cells.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Implantação do Embrião
/
Prolactina
/
Ratos
/
Útero
/
Feminino
/
Gravidez
/
Bromocriptina
/
Desenvolvimento Embrionário
/
Glutamina-Frutose-6-Fosfato Transaminase (Isomerizante)
/
Tamanho da Ninhada de Vivíparos
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
1993
Tipo de documento:
Artigo
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