Effect of cyproterone acetate on testis of albino rats: ultrastructural and biochemical approach.
Indian J Exp Biol
;
1990 Mar; 28(3): 201-7
Artigo
em Inglês
| IMSEAR
| ID: sea-61800
ABSTRACT
The animals were treated with cyproterone acetate (1 mg/100 g body weight) for 60 days after which the testicular tissue was studied at the ultrastructural level to determine the stage at which the effect took place and to study the magnitude of the effect. The testis showed changes in Sertoli cells, Leydig cells, germ cells and in the spermatids. To correlate these changes, important marker enzymes and other biochemical parameters essential for spermatogenesis were studied after 30 days and 60 days of the treatment. They registered a decrease in their levels as compared with the controls.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Ratos
/
Ratos Endogâmicos
/
Células de Sertoli
/
Testículo
/
Masculino
/
Microscopia Eletrônica
/
Acetato de Ciproterona
/
Ciproterona
/
Antagonistas de Androgênios
/
Células Intersticiais do Testículo
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
1990
Tipo de documento:
Artigo
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