Tumor necrosis factor alpha and interleukin 6 in infants with sepsis.
Indian Pediatr
;
2005 Oct; 42(10): 1024-8
Artigo
em Inglês
| IMSEAR
| ID: sea-6209
ABSTRACT
Thirty-two infants above one month of age admitted to a tertiary care hospital with signs of infection and presumptive diagnosis of sepsis were included. Cytokine levels of tumor necrosis factor alpha (TNFmu) and interleukin-6 (IL 6) were estimated at admission and after 48 to 72 hr, and their relationship examined to the outcome. Significantly higher TNFalpha and IL-6 levels were seen in infants with sepsis compared to control. The TNFalpha levels significantly decreased in patients with sepsis, septic shock and the survivors, while the patients who did not survive, the levels showed no significant change after 48 hr. The initial levels of IL6 were comparatively higher in patients with septic shock and non-survivors, and increased at 48 hr of admission in patients with sepsis, septic shock and non-survivors.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Prognóstico
/
Choque Séptico
/
Feminino
/
Humanos
/
Masculino
/
Biomarcadores
/
Estudos de Casos e Controles
/
Estudos Prospectivos
/
Interleucina-6
/
Fator de Necrose Tumoral alfa
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Indian Pediatr
Ano de publicação:
2005
Tipo de documento:
Artigo
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