Characterization of toxin from cheilanthes fern and its effect on lymphocyte proliferation and DNA fragmentation.
Indian J Exp Biol
;
2001 Oct; 39(10): 1065-7
Artigo
em Inglês
| IMSEAR
| ID: sea-62395
ABSTRACT
Thin layer chromatography of aqueous extract of whole Cheilanthesfarinosa fern indicated the presence of ptaquiloside or ptaquiloside like compound, coinciding Rf values with that of Pterosin B standard. HPLC analysis revealed the presence of 26.3 mg/kg ptaquiloside. In vitro studies of the aqueous extract on lymphocyte culture revealed a correlation between stimulative indices and concentration of aqueous extract. Stimulation in lymphocyte proliferation was in order of bracken > cheilanthes > ConA> ptaquiloside standard. On incubation of lymphocyte with aqueous extract of ferns, no DNA damage was observed in isolated DNA.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Plantas Tóxicas
/
Sais de Tetrazólio
/
Bovinos
/
Extratos Vegetais
/
Ativação Linfocitária
/
Linfócitos
/
Cromatografia Líquida de Alta Pressão
/
Cromatografia em Camada Fina
/
Gleiquênias
/
Fragmentação do DNA
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
2001
Tipo de documento:
Artigo
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