Antiulcerogenic activity of Satavari mandur--an Ayurvedic herbo-mineral preparation.
Indian J Exp Biol
;
2002 Oct; 40(10): 1173-7
Artigo
em Inglês
| IMSEAR
| ID: sea-62428
ABSTRACT
Satavari mandur (SM) is a herbo-mineral preparation containing Asparagus racemosus, which finds mention in ancient Indian texts for treatment of gastric ulcers. The ulcer protective effect of SM, 125-500 mg/kg given orally, twice daily for three, five and seven days, was studied on cold restraint stress-induced gastric ulcer in rats. The effective regimen was found to be 250 mg/kg given for five days and hence was used for further experiments. SM showed significant protection against acute gastric ulcers induced by pyloric ligation but was ineffective against aspirin- and ethanol-induced ulcers. Further, gastric juice studies showed that, SM significantly increased the mucosal defensive factors like mucus secretion, but had little or no effect on offensive factors like acid and pepsin secretion.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Ratos
/
Feminino
/
Masculino
/
Liliaceae
/
Relação Dose-Resposta a Droga
/
Animais
/
Ayurveda
/
Antiulcerosos
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
2002
Tipo de documento:
Artigo
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