Hepatoprotective activity of Trichopus zeylanicus extract against paracetamol-induced hepatic damage in rats.
Indian J Exp Biol
;
1998 Apr; 36(4): 385-9
Artigo
em Inglês
| IMSEAR
| ID: sea-63338
ABSTRACT
Trichopus zeylanicus extract has been evaluated for its antihepatotoxic and choleretic activities in rats. The plant leaf suspension (1000 mg/kg; wet weight) as well as its methanol extract (100 mg/kg) showed a remarkable hepatoprotective activity against paracetamol-induced hepatotoxicity as judged from the serum marker enzymes, liver histology and levels of lipid peroxides in liver. The effect of the methanol extract was found to be concentration dependent. The water and hexane extracts were almost inactive. The methanol extract (100 mg/kg) also exhibited choleretic activity in anesthetized normal rats. In short, we report here for the first time the antihepatotoxic as well as choleretic properties of T. zeylanicus.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Ratos
/
Masculino
/
Extratos Vegetais
/
Ratos Wistar
/
Doença Hepática Induzida por Substâncias e Drogas
/
Animais
/
Acetaminofen
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
1998
Tipo de documento:
Artigo
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