Isolation, characterization and optimization of antifungal activity of an actinomycete of soil origin.
Indian J Exp Biol
;
2004 Sep; 42(9): 928-32
Artigo
em Inglês
| IMSEAR
| ID: sea-63364
ABSTRACT
About 312 actinomycetes were isolated from soil samples on chitin agar. All these isolates were purified and screened for their antifungal activity against pathogenic fungi. Out of these, 22% of the isolates exhibited activity against fungi. One promising isolate with strong antifungal activity against pathogenic fungi was selected for further studies. This isolate was from Pune, and was active against both yeasts and molds. Various fermentation parameters were optimized. Based on morphological and biochemical parameters, the isolate was identified as Streptomyces. The correlation of antifungal activity with growth indicated growth dependent production of antimetabolite. Maximum antifungal metabolite production (600 units/ml) was achieved in the late log phase, which remained constant during stationery phase, and it was extracellular in nature.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Solo
/
Microbiologia do Solo
/
Streptomyces
/
Testes de Sensibilidade Microbiana
/
Actinobacteria
/
Fungos
/
Antibiose
/
Antifúngicos
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
2004
Tipo de documento:
Artigo
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