Role of magnification endoscopy in the diagnosis and evaluation of suspected celiac disease: correlation with histology.
Artigo
em Inglês
| IMSEAR
| ID: sea-63702
ABSTRACT
BACKGROUND:
Magnification endoscopy (ME), with 115-fold magnification, allows visualization of duodenal villi. We assessed the efficacy of ME for evaluation of villous atrophy.METHODS:
ME and duodenal biopsy were done in 16 patients with suspected celiac disease and 16 control subjects undergoing endoscopy for reflux symptoms. The pathologist was unaware of the ME findings.RESULTS:
Sensitivity, specificity and positive and negative predictive values for villous atrophy (partial or total) were 100%, 91%, 83% and 100%, respectively. Corresponding values for normal villous structure were 91%, 100%, 100% and 83%, respectively. There was significant concordance between the ME and histology findings.CONCLUSION:
ME is a reliable technique to diagnose villous atrophy.
Texto completo:
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Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Atrofia
/
Biópsia
/
Feminino
/
Humanos
/
Masculino
/
Aumento da Imagem
/
Doença Celíaca
/
Sensibilidade e Especificidade
/
Duodenoscopia
/
Adulto
Tipo de estudo:
Estudo diagnóstico
/
Estudo prognóstico
Idioma:
Inglês
Ano de publicação:
2007
Tipo de documento:
Artigo
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