Factor V Leiden is not commonly associated with idiopathic portal vein thrombosis in southern India.
Artigo
em Inglês
| IMSEAR
| ID: sea-64155
ABSTRACT
BACKGROUND:
Factor V Leiden has been reported in 2%-30% of patients with portal vein thrombosis. This wide variation makes it difficult to assess the importance of factor V Leiden as a predisposing factor.METHODS:
Factor V Leiden was determined by restriction fragment length polymorphism in 112 patients with portal vein thrombosis, 104 with deep vein thrombosis and 98 control subjects.RESULTS:
Only 3/112 (3%) patients with portal vein thrombosis had factor V Leiden, compared to 1/98 (1%) controls and 16/104 (15%) with deep vein thrombosis; of these, 3, 1 and 15, respectively, were heterozygous for this mutation.CONCLUSION:
Factor V Leiden contributes little, if at all, to the development of portal vein thrombosis in southern India.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Veia Porta
/
Veia Esplênica
/
Polimorfismo de Fragmento de Restrição
/
Idoso
/
Feminino
/
Humanos
/
Masculino
/
Fator V
/
Criança
/
Pré-Escolar
País/Região como assunto:
Ásia
Idioma:
Inglês
Ano de publicação:
2006
Tipo de documento:
Artigo
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