Immunogenicity of yeast-derived hepatitis B vaccine in Pakistani adults.
Artigo
em Inglês
| IMSEAR
| ID: sea-64603
ABSTRACT
A study of the immunogenicity and safety of 20 micrograms recombinant DNA yeast derived hepatitis B vaccine was conducted in 153 Pakistani adults. All participants were in good physical condition, had negative hepatitis B serological markers (HBsAg, anti-HBs, anti-HBc) and normal ALT. Anti-HBs developed in 33%, 81% and 98% of subjects one month after the first, second and third dose respectively. Minor systemic and local side-effects were observed in 39% of individuals. We conclude that yeast derived hepatitis B vaccine is safe, effective and immunogenic in Pakistani adults.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Paquistão
/
Leveduras
/
Feminino
/
Humanos
/
Masculino
/
DNA Recombinante
/
Vacinas contra Hepatite Viral
/
Vacinas Sintéticas
/
Adolescente
/
Vacinação
País/Região como assunto:
Ásia
Idioma:
Inglês
Ano de publicação:
1990
Tipo de documento:
Artigo
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