Percutaneous sonography-guided fine needle aspiration biopsy of colonoscopic biopsy-negative colonic lesions.
Artigo
em Inglês
| IMSEAR
| ID: sea-64751
ABSTRACT
BACKGROUND:
Pre-operative tissue diagnosis with colonoscopy is not always possible in patients with colonic lesions.OBJECTIVE:
To study the usefulness and efficacy of percutaneous ultrasound-guided aspiration biopsy of colonic lesions.METHODS:
Fifty consecutive patients with colonic lesions in whom colonoscopic brush cytology and biopsy were either negative or the lesion was not accessible on colonoscopy on two attempts, underwent percutaneous ultrasound-guided fine-needle aspiration biopsy. The results were compared with surgical findings.RESULTS:
Fine-needle aspiration biopsy revealed adenocarcinoma in 40 patients; one had lymphoma, 2 had tuberculosis, 2 had abscess and 5 patients had negative aspiration. Forty-eight patients (excluding 2 with tuberculosis) underwent laparotomy and the diagnoses on aspiration biopsy were confirmed. Of the 5 negative aspirations, 3 had adenocarcinoma, one had tuberculosis and one intussusception. Thus, we had sensitivity of 91.8%, specificity of 100%, predictive value of positive results 100%, predictive value of negative results 20%, and percentage of false negative results 8.1%. Two patients developed complications--hemorrhage into the peritoneum and sepsis due to perforation at the site of aspiration; both survived after surgery.CONCLUSION:
Percutaneous ultrasound-guided aspiration biopsy may be attempted for diagnosis of colonic lesions in situations where it may be the only means of obtaining a cytological diagnosis before surgery.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Biópsia por Agulha
/
Feminino
/
Humanos
/
Masculino
/
Adenocarcinoma
/
Valor Preditivo dos Testes
/
Ultrassonografia
/
Sensibilidade e Especificidade
/
Colonoscopia
/
Colo
Tipo de estudo:
Estudo diagnóstico
/
Estudo prognóstico
Idioma:
Inglês
Ano de publicação:
1999
Tipo de documento:
Artigo
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