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Intussusception in southern Indian children: lack of association with diarrheal disease and oral polio vaccine immunization.
Artigo em Inglês | IMSEAR | ID: sea-65015
ABSTRACT

BACKGROUND:

Intussusception is the most common cause of intestinal obstruction in young children and has been reported as a complication of a recently withdrawn tetravalent reassortant rotavirus vaccine.

METHODS:

We studied the history, clinical presentation, management and outcome of intussusception presenting to a tertiary care hospital in southern India over a 10-year period, in order to assess potential association with diarrheal disease and immunization.

RESULTS:

Data from 137 index cases and 280 control subjects indicated that the risk of diarrheal disease or oral polio vaccine administration in the month prior to presentation was similar in the index cases and controls. Mean time to presentation to hospital after developing symptoms was 1.8 days, and 77.3% of patients required surgery, with 47.4% undergoing intestinal resection. Mortality was 0.006%.

CONCLUSIONS:

No association could be demonstrated between gastroenteritis or oral poliovirus vaccine immunization and intussusception in southern Indian children. These children presented later and required operative intervention more frequently than has been reported in other studies, but had a good outcome with low mortality.
Assuntos
Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Assunto principal: Poliomielite / Feminino / Humanos / Masculino / Vacina Antipólio Oral / Estudos de Casos e Controles / Pré-Escolar / Proteção da Criança / Estudos Retrospectivos / Imunização Tipo de estudo: Estudos de avaliação / Estudo observacional / Fatores de risco País/Região como assunto: Ásia Idioma: Inglês Ano de publicação: 2003 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Assunto principal: Poliomielite / Feminino / Humanos / Masculino / Vacina Antipólio Oral / Estudos de Casos e Controles / Pré-Escolar / Proteção da Criança / Estudos Retrospectivos / Imunização Tipo de estudo: Estudos de avaliação / Estudo observacional / Fatores de risco País/Região como assunto: Ásia Idioma: Inglês Ano de publicação: 2003 Tipo de documento: Artigo