Dental plaque: an unlikely reservoir of Helicobacter pylori.
Artigo
em Inglês
| IMSEAR
| ID: sea-65281
ABSTRACT
BACKGROUND AND AIM:
Dental plaque has been suggested as a reservoir for Helicobacter pylori, though data in this regard are conflicting. We evaluated the prevalence of H. pylori DNA in dental plaque using polymerase chain reaction (PCR).METHODS:
Antral H. pylori status of 156 patients with acid-peptic disease (APD) was studied by rapid urease test (RUT), histology and culture. Dental plaque obtained from these 156 patients and 92 healthy volunteers was evaluated for the presence of H. pylori using RUT, culture and PCR.RESULTS:
H. pylori was present in 133 antral biopsy samples by RUT and/or histology. The dental plaque of 37 patients with APD and 21 healthy volunteers tested positive by RUT. H. pylori was not isolated by culture from any of the dental plaques. PCR gave a significant amplification product in 11 of 248 (4.4%) dental plaque samples, 7 from patients with APD and 4 from normal healthy volunteers.CONCLUSION:
The frequency of H. pylori in the dental plaque is low, and this is unlikely to be a prominent site of infection with H. pylori.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Feminino
/
Humanos
/
Masculino
/
Reservatórios de Doenças
/
Estudos de Casos e Controles
/
Reação em Cadeia da Polimerase
/
Prevalência
/
Helicobacter pylori
/
Infecções por Helicobacter
/
Primers do DNA
Tipo de estudo:
Estudo observacional
/
Estudo de prevalência
/
Fatores de risco
Idioma:
Inglês
Ano de publicação:
1998
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS