Dilatation of radiation-induced esophageal strictures under sublingual buprenorphine analgesia: a pilot study.
Artigo
em Inglês
| IMSEAR
| ID: sea-65420
ABSTRACT
BACKGROUND:
Pain during dilatation of radiation strictures is a troublesome complaint. There is little information on sedation and analgesia during this procedure. We performed a pilot study to compare the analgesic efficacy of sublingual buprenorphine and intravenous pentazocine during dilatation of radiation-induced esophageal strictures.METHODS:
Thirty-one patients with esophageal cancer who had radiation-induced strictures were randomized to receive either buprenorphine 0.2 mg sublingually two hours before dilatation (n = 17) or pentazocine 30 mg intravenously five minutes before dilatation (n = 14). Dilatation was considered successful if it could be performed to 12 mm diameter or more. Pain experienced during dilatation was graded as mild, moderate or severe.RESULTS:
Sixteen patients in the buprenorphine group and 12 in the pentazocine group were dilated to > 12 mm size (p = ns). Twelve and nine patients respectively in the two groups experienced mild or no pain; ten and six patients had minor side-effects (p = ns).CONCLUSION:
Buprenorphine is useful for sedoanalgesia during dilatation of radiation-induced strictures of the esophagus.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Pentazocina
/
Lesões por Radiação
/
Idoso
/
Buprenorfina
/
Feminino
/
Humanos
/
Masculino
/
Neoplasias Esofágicas
/
Administração Sublingual
/
Projetos Piloto
Tipo de estudo:
Ensaio Clínico Controlado
/
Estudo diagnóstico
/
Estudo observacional
Idioma:
Inglês
Ano de publicação:
1997
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS