Role of myeloperoxidase index in differentiation of megaloblastic and aplastic anemia.
Indian J Med Sci
;
2004 Aug; 58(8): 345-8
Artigo
em Inglês
| IMSEAR
| ID: sea-66203
ABSTRACT
BACKGROUND:
Elevated neutrophil myeloperoxidase may have a role in the diagnosis of megaloblastic erythropoiesis.AIMS:
To study the differentiating role of myeloperoxidase index in megaloblastic and aplastic anemia. SETTINGS ANDDESIGN:
The myeloperoxidase index (MPXI) was studied in 96 patients with megaloblastic and aplastic anemia diagnosed on bone marrow aspiration and biopsy examinations. METHODS AND MATERIALS MPXI was measured with Technicon H1 (Bayer) automated analyzer. Nonparametric Mann-Whitney statistical test was used to compare the MPXI values between groups.RESULTS:
The mean MPXI in megaloblastics and aplastic anemia was 18.3 and 1.8 (p< 0.001) respectively. MPXI> 20 denoted megaloblastic and MPXI <-11.6 denoted aplastic anemia.CONCLUSION:
MPXI measurement may assist differentiation of megaloblastic from aplastic anemia, while MPXI> 20 rules out aplastic and MPXI <-11.6 rules out megaloblastic anemia.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Idoso
/
Feminino
/
Humanos
/
Masculino
/
Criança
/
Adolescente
/
Peroxidase
/
Adulto
/
Diagnóstico Diferencial
/
Ensaios Enzimáticos Clínicos
Tipo de estudo:
Estudo diagnóstico
Idioma:
Inglês
Revista:
Indian J Med Sci
Ano de publicação:
2004
Tipo de documento:
Artigo
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