Choriocarcinoma with negative urinary and serum beta human chorionic gonadotropin (betaHCG)--a case report.
Indian J Med Sci
;
2005 Dec; 59(12): 538-41
Artigo
em Inglês
| IMSEAR
| ID: sea-66734
ABSTRACT
This was a rare case where a patient presented clinically as a case of post abortal sepsis and ultrasound showing the picture of an intramural degenerating fibroid. Her serum and urine both were negative for beta human chorionic gonadotropin (betaHCG). Patient succumbed to choriocarcinoma 1 month later. Failure to detect urinary and serum betaHCG lead to maternal mortality due to the choriocarcinoma. The failure to detect, certain degradation products of HCG which may predominate in gestational trophoblastic neoplasia, by many common HCG testing kits lead to the error of diagnosis. Only 3 of the 7 common commercial serum HCG tests appropriately detects nicked HCG and its free betaHCG, DPC immulite assay, being the most sensitive method. Though of rare occurrence, this awareness is important for diagnosis and follow-up of gestational trophoblastic neoplasia and could have been life saving in our case.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Neoplasias Uterinas
/
Feminino
/
Humanos
/
Gravidez
/
Biomarcadores
/
Coriocarcinoma
/
Evolução Fatal
/
Gonadotropina Coriônica Humana Subunidade beta
/
Adulto
/
Diagnóstico Diferencial
Tipo de estudo:
Estudo diagnóstico
Idioma:
Inglês
Revista:
Indian J Med Sci
Ano de publicação:
2005
Tipo de documento:
Artigo
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