Prevalence and extent of glycemic excursions in well-controlled patients with type 2 diabetes mellitus using continuous glucose-monitoring system.
Indian J Med Sci
;
2009 Feb; 63(2): 66-71
Artigo
em Inglês
| IMSEAR
| ID: sea-67328
ABSTRACT
BACKGROUND:
Continuous glucose-monitoring system (CGMS) is a tool for assessment of glycemic excursions. Glucose variability is a risk factor independent of glycosylated hemoglobin (HbA1c) for diabetic complications; hence CGMS may be a better method for management of diabetes.AIM:
To evaluate the extent of glycemic excursions in well-controlled type 2 diabetic patients. SETTING ANDDESIGN:
The study was carried out in 21 diabetic patients on oral agents. MATERIALS ANDMETHODS:
Patients underwent continuous glucose-monitoring by CGMS for 3 days. Number and duration of glycemic excursions, correlation coefficient (%) between CGMS and self-monitoring blood glucose (SMBG), mean absolute difference (%MAD) and complications of CGMS were analyzed. STATISTICAL ANALYSES The statistical analyses were performed with the use of mean +/- SD, t-test and Mann-Whitney test.RESULTS:
The mean age of patients was 51.9 +/- 9.7 years. The mean HbA1c was 6.7 +/- 0.38%. The mean number of glycemic readings was 753.6 +/- 203.5 times. The correlation coefficient was 0.83 and the MAD was 11.7 +/- 8.0%, which were considerable. Three (14.2%) patients experienced, altogether, 9 hypoglycemic events with an average duration of 162 minutes. Twenty (94.7%) patients had hyperglycemic events. The mean duration of hyperglycemia was 19.4 +/- 12.8 hours. All events were asymptomatic. Disconnection of device was the most common complication (3 patients).CONCLUSION:
This study demonstrated that well-controlled type 2 diabetic patients have a considerable number of hypoglycemia and hyperglycemia events that may be missed by SMBG.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Feminino
/
Humanos
/
Masculino
/
Hemoglobinas Glicadas
/
Automonitorização da Glicemia
/
Prevalência
/
Fatores de Risco
/
Estatística como Assunto
/
Monitorização Ambulatorial
/
Diabetes Mellitus Tipo 2
Tipo de estudo:
Estudo de etiologia
/
Estudo de prevalência
/
Fatores de risco
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Indian J Med Sci
Ano de publicação:
2009
Tipo de documento:
Artigo
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